PET/MRI for Neurologic Applications

Advantages of PET/MRI are presented, specifically noting how the novel imaging modality may be beneficial in neurologic applications.

Course ID: Q00392 Category:
Modalities: , ,

2.75

Satisfaction Guarantee

$29.00

Targeted CE per ARRT’s Discipline, Category, and Subcategory classification for enrollments starting after August 22, 2024:
[Note: Discipline-specific Targeted CE credits may be less than the total Category A credits approved for this course.]

Computed Tomography: 0.25
Procedures: 0.25
Head, Spine, and Musculoskeletal: 0.25

Magnetic Resonance Imaging: 1.25
Patient Care: 0.25
Patient Interactions and Management: 0.25
Procedures: 1.00
Neurological: 1.00

Nuclear Medicine Technology: 1.25
Procedures: 1.25
Other Imaging Procedures: 1.25

Registered Radiologist Assistant: 0.75
Patient Care: 0.25
Pharmacology: 0.25
Procedures: 0.50
Neurological, Vascular, and Lymphatic Sections: 0.50

Outline

  1. Introduction
  2. Methodologic and Scientific Advantages
  3. MRI-Based PET Motion Correction
    1. Partial-Volume Effect (PVE) Correction
    2. Image-Based Radiotracer AIF Estimation
    3. Technique Cross-Calibration and Validation
  4. Advantages of Simultaneous PET/MRI in Clinical and Research Applications
    1. Brain Tumors
    2. Dementia/Neurodegeneration
    3. Stroke/Cerebrovascular Disorders
    4. Epilepsy
    5. Neurobiology of Brain Activation
    6. Translational Research
  5. Conclusion

Objectives

Upon completion of this course, students will:

  1. identify the indicators of changes in brain hemodynamics
  2. recognize a common source of motion during neurologic PET imaging
  3. identify the categories of uncooperative patients that can benefit from simultaneous PET/MRI
  4. understand the factors that affect tissue activity concentration on PET images
  5. recognize the brain structure most often affected by partial volume effects
  6. identify the factor affecting the accuracy of PVE correction that is eliminated by simultaneous PET/MRI acquisition
  7. identify the gold standard for determining the arterial input function
  8. identify the gold standard for measuring cerebral blood flow
  9. describe the performance of functional MRI using BOLD imaging sequences
  10. explain the neurologic concept of the brain baseline state
  11. indicate the MRI techniques being used to investigate brain connectivity
  12. identify the PET tracer used to measure metabolism
  13. describe the magnetic properties of gadolinium-based contrast agents
  14. list the types of MR images suitable for GBCA enhancement
  15. explain the semi-quantitative measurement cerebral blood flow
  16. explain the semi-quantitative measurement cerebral blood volume
  17. describe the magnetic properties of oxyhemoglobin and deoxyhemoglobin
  18. list ways that MRI assesses brain anatomy
  19. list the factors that affect contrast enhancement of MR images
  20. identify the PET tracer used to evaluate cellular proliferation
  21. identify the PET tracer used to evaluate tissue hypoxia
  22. recognize the most aggressive and fatal brain tumor
  23. understand barriers preventing the use of novel MRI techniques in the evaluation of cognitive impairment or suspected dementia
  24. identify the PET tracer used to evaluate amyloid deposition
  25. identify the gold standard for noninvasively identifying brain regions associated with ischemic stroke
  26. list the categories of PET tracers that are most useful in the acute phase of ischemic stroke
  27. indicate the time window during which patient are most likely to benefit from therapeutic interventions following ischemic stroke
  28. list the benefits to patients from the use of integrated PET/MRI systems
  29. describe the fastest-acting cells in the human body
  30. indicate the physical half-life of the isotope carbon-11